Yes, really, if our interests include making sure Al-Qaeda-aligned Islamist groups don't gain control of Syria, and preventing the ensuing ethno-religious cleansing.
However, eventually, everyone of this despots is overthrown and chaos ensues. There is no a priori reason to believe that chaos later is better than chaos now.
So, what course of action do you support? Because supporting the toppling of Assad will almost certainly lead to the above. Unless you support the US invading and occupying Syria with the hundreds of thousands of troops required to keep the peace. Indefinitely.
I support funding/arming/training/supporting secular (slightly socialist) Kurdish groups, but everyone else can fuck off. Especially Turkey.