Can covid-19 like viruses be beaten without antibodies produced?

[repoman]

What non antibody immune system responses would kill it?

How often would this happen?

Also since antibodies are all tailor made by definition, how can a test be sure that a negative antibody test just did not test for the one YOU produced?

There has to be a somewhat narrow design tolerance of a working antibody for covid-19, but is that still too wide to always show up in a test?

If I am asking naive questions about this I am not alone in my current limitation of knowldge.


Ok, let me get in another area of the Venn diagram. Is Covid-19 a virus that is difficult for many people to make effective antibodies against?

 

[Loren Pechtel]

Moot question.

They have demonstrated that in monkeys infection produces resistance.

 

[J842P]

Also since antibodies are all tailor made by definition, how can a test be sure that a negative antibody test just did not test for the one YOU produced?

There has to be a somewhat narrow design tolerance of a working antibody for covid-19, but is that still too wide to always show up in a test?

No clinical test is ever 100% sure. A key point to understand is that typically, your body makes many different strains of antibodies against various epitopes on whatever antigen it's responding to. Part of coming up with an antibody test is coming up with some epitope that some reliable percentage of people will produce antibodies for.

And there are always false positives and false negatives.

 

[barbos]

What non antibody immune system responses would kill it?

How often would this happen?

https://en.wikipedia.org/wiki/Interferon
It always happens, not always able to fight it off completely.

Also since antibodies are all tailor made by definition, how can a test be sure that a negative antibody test just did not test for the one YOU produced?

Good question, you should send your questions to Dr. Fauci.
I think they have dead virus or simply virus proteins in their test kit and see if there is anything in your blood which sticks to it. If it sticks it's by definition an antibody.

Ok, let me get in another area of the Venn diagram. Is Covid-19 a virus that is difficult for many people to make effective antibodies against?

I don't think it's the reason, I think it's the fact that people die before being able to get through it.