What would it even mean to 'manipulate time and space?' Time travel? Warp drive?
Being able to go from Sydney to London in a day, rather than several weeks? Being able to talk to someone in Manhattan from your office in Los Angeles in real time, rather than wait for an exchange of letters, or of telegrams?
All of human progress since the Industrial Revolution has been underpinned by the minimisation of the time constraints imposed by spatial distance, culminating in high bandwidth fibre optics, supersonic air travel, and containerized multi-modal freight.
Communications have now run into physical law - The latency between antipodal sites cannot be much further reduced. Even if we develop neutrino based communications that can travel a straight line rather than hugging the surface of the planet the saving is tiny. Reducing latency from ~60 milliseconds to ~20ms is hardly comparable to reducing it to ~60ms from 250 days (21,600,000,000ms), which is how long it took to get a message half way around the planet a mere 250 years ago.
Transport of people and goods still has some more significant potential for improvement, though we seem to have been going backwards ever since Concorde was retired and not replaced. New York to London in seven hours is significantly slower than the same trip in three hours.
I would certainly be much happier if I could visit my family via a ten hour supersonic flight, or a two hour sub-orbital one, rather than spending 24-30 hours on subsonic aircraft. But at least it's not eight months on a ship anymore.