Underseer
Contributor
Mostly, I'm just excited that Potholer54 finally made another video. His videos tend to be unusually well-researched.
Mostly, I'm just excited that Potholer54 finally made another video. His videos tend to be unusually well-researched.
[B]Pusztai affair[/B]
The experiment as reported in The Lancet – if taken at face value – found that the transformation event or the gene construct produced one compound that is heat stable and that made the jejunum proliferate but had no effect on the caecum. And it also found that – at the same time – the transformation event or the gene construct produced another compound that is heat activated that had an anti-proliferation effect on the caecum but no effect on the jejunum.
A survey by the European Food Safety Authority <(2008)>* GMO Panel Working Group on Animal Feeding Trials concluded that "Results obtained from testing GM food and feed in rodents indicate that large (at least 100-fold) 'safety' margins exist between animal exposure levels without observed adverse effects and estimated human daily intake. The studies did not show any biologically relevant differences in the parameters tested between control and test animals."[33]
* my date insert
all the above and yet ....
5. The trials carried out by Dr Pusztai consisted of 4 feeding groups of rats. Each group was fed respectively the same amount of the isocaloric (having the same energy value) and iso-proteinic (having the same amount of protein) diets.
In experiment A (published as Ewen and Pusztai, 1999. Effect of diets containing genetically modified potatoes expressing Galanthus nivalis lectin on rat small intestine. Lancet 354:1353-4), the four diets were as follows:
(i) normal, non-GM parent line of potatoes
(ii) normal, non-GM parent line of potatoes spiked with GNA lectin
(iii) GNA GM potatoes
(iv) LA (lactalbumin) protein diet, for healthy growth, as an internal control.
The lymphocytes of rats fed with these diets were challenged with ConA lectin (Concanavalin A, a protein found in jack-beans) and PHA lectin (phytohemagglutinin, a protein found in legumes), but this part of the experiment did not form part of the publication in The Lancet.
In a separate experiment (experiment B), which the researchers carried out earlier and which was not published in a journal, the same amount of the following isoproteinic and isoproteinic diets were fed to rats:
(i) LA (lactalbumin protein) as an internal control
(ii) Lactalbumin spiked with ConA
(iii) Lactalbumin spiked with the same amount of GNA as was the ConA
(iv) non-GM potato spiked with GNA
(v) non-GM potato spiked with ConA
In all other respects the diets were equivalent. So if there was any inadequacy in the GNA GM potato feeding group diet, this would have been the same in all groups and therefore a constant. Some have commented that “feeding growing rodents raw potato would cause serious damage to their growth”. However, this is, in fact, a non-argument, since raw potatoes were fed to all experimental groups and would therefore have been expected to produce adverse effects even in the negative non-GM potato feeding group.
Comparing experiments A and B, the weight, sex, and age of all rats were the same, as was the amount of feed given to each animal and the length of the experiment. The two experiments showed the same growth curve, and internal organ weight and all other parameters were identical in the LA (internal control) groups. On this basis the two treatments (ConA and GNA) could be compared, but they were not part of the same experiments.
Only 2 groups from these two experiments showed adverse effects:
(ii) From experiment A, those fed the GNA GM potatoes – implying that the GM transformation process (tissue culture plus gene insertion procedure) had produced a line of potato with unexpected toxic effects.
(i) From experiment B, those fed the Con A spiked normal potatoes, which was as expected for a known toxin and therefore acted as a good positive control (in which a substance already known to be toxic is fed to a group of animals to test whether the experimental design is sensitive enough to detect the toxic effects). This result in combination with the lack of adverse effects with the non-GM and the non-GM + GNA feeding groups confirmed the soundness of the overall experimental design;
In neither experiment were GM ConA potatoes tested. The researchers had the GM ConA potatoes ready, but they were not allowed to carry out that experiment.
[B]Pusztai affair[/B]
The experiment as reported in The Lancet – if taken at face value – found that the transformation event or the gene construct produced one compound that is heat stable and that made the jejunum proliferate but had no effect on the caecum. And it also found that – at the same time – the transformation event or the gene construct produced another compound that is heat activated that had an anti-proliferation effect on the caecum but no effect on the jejunum.
A survey by the European Food Safety Authority <(2008)>* GMO Panel Working Group on Animal Feeding Trials concluded that "Results obtained from testing GM food and feed in rodents indicate that large (at least 100-fold) 'safety' margins exist between animal exposure levels without observed adverse effects and estimated human daily intake. The studies did not show any biologically relevant differences in the parameters tested between control and test animals."[33]
* my date insert
all the above and yet ....
Do you think Wikipedia is a good place to link to?
[B]Pusztai affair[/B]
The experiment as reported in The Lancet – if taken at face value – found that the transformation event or the gene construct produced one compound that is heat stable and that made the jejunum proliferate but had no effect on the caecum. And it also found that – at the same time – the transformation event or the gene construct produced another compound that is heat activated that had an anti-proliferation effect on the caecum but no effect on the jejunum.
A survey by the European Food Safety Authority <(2008)>* GMO Panel Working Group on Animal Feeding Trials concluded that "Results obtained from testing GM food and feed in rodents indicate that large (at least 100-fold) 'safety' margins exist between animal exposure levels without observed adverse effects and estimated human daily intake. The studies did not show any biologically relevant differences in the parameters tested between control and test animals."[33]
* my date insert
all the above and yet ....
Do you think the editorialising in Wikipedia is a good place to link to?
The least credible is the video you posted. Seriously, what is the point of taking on the weakest opponents and claiming victory?Do you think Wikipedia is a good place to link to?
If it's between Wikipedia and a web site called "GMwatch.org"?
Which do you think is more credible?
The least credible is the video you posted. Seriously, what is the point of taking on the weakest opponents and claiming victory?If it's between Wikipedia and a web site called "GMwatch.org"?
Which do you think is more credible?
But a major problem is that they keep telling us that companies like Monsanto are engaged in science when they do this or that test.
Science is a neutral investigation. It doesn't care what it finds.
Monsanto's job is not to investigate but to sell it's products. Yet we keep being assured that what they do is "science". Your video makes that rather obvious mistake.
Yes, as it needs be neutral.If that is a mistake, then it implies that no organisation that sells products can ever do science.The least credible is the video you posted. Seriously, what is the point of taking on the weakest opponents and claiming victory?
But a major problem is that they keep telling us that companies like Monsanto are engaged in science when they do this or that test.
Science is a neutral investigation. It doesn't care what it finds.
Monsanto's job is not to investigate but to sell it's products. Yet we keep being assured that what they do is "science". Your video makes that rather obvious mistake.
If it's not neutral investigation then can it be science?That eliminates almost all of the science that has ever been done from qualifying as science in your book,
But can we assume someone is neutral if they are being paid by that company?which seems rather extreme.
Yes, as it needs be neutral.If that is a mistake, then it implies that no organisation that sells products can ever do science.
If it's not neutral investigation then can it be science?That eliminates almost all of the science that has ever been done from qualifying as science in your book,
A)Yes
B)No
But can we assume someone is neutral if they are being paid by that company?which seems rather extreme.
Ahhh...but I didn't say it did. I asked whether we could just assume they were being neutral investigators. And that is a very different thing.Getting a pay packet does not imply nor require slavish obedience to the company that employs you.
Ahhh...but I didn't say it did. I asked whether we could just assume they were being neutral investigators. And that is a very different thing.Getting a pay packet does not imply nor require slavish obedience to the company that employs you.
Rubbish.Different or not, the answer is yes.Ahhh...but I didn't say it did. I asked whether we could just assume they were being neutral investigators. And that is a very different thing.
Unless you have solid evidence that an individual researcher or group is biased.
Bandying around generalised slanders against scientists is really very ugly behaviour, .
Rubbish.Different or not, the answer is yes.
Unless you have solid evidence that an individual researcher or group is biased.
Bandying around generalised slanders against scientists is really very ugly behaviour, .
I have every right to question whether a scientist producing a report, being paid by Monsanto saying a GMO is safe to eat is biased.
To clarify this would apply to any scientist working for any company that is producing a product that is crucial to that companies survival.
The alternative is ridiculous. The alternative is that we must assume that scientists who work for Monsanto are some kind of gods who can never be compromised![]()
That was rather dramaticIf we are to treat everybody as you treat those scientists who work for Monsanto, then we cannot trust a word anyone says, and further debate is futile.
That was rather dramaticIf we are to treat everybody as you treat those scientists who work for Monsanto, then we cannot trust a word anyone says, and further debate is futile.![]()
No, more drama than logicIt is a logical consequence of your stated position.That was rather dramatic![]()