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"Coronavirus and the US" or "We are all going to die!!!!"

 
 
 
southernhybrid said:
lpetrich said:
People who ignore social distancing rules may have psychopathic personality traits, study finds

The results:
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If that's true, most of the people in my small city have psychopathic traits. I think I refer to it more as ignorance or denial. I tried to convince a nurse friend that she should keep wearing her mask when she goes to the store etc. She is a Trump supporter and a conservative Christian. I've never thought of her as a psychopath, just a clueless victim of brainwashing.
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Trump supporter and conservative christian? Almost definitely a sociopath (not psychopath, if I remember the distinction correctly).
 
Psychopathic or sociopathic? Isn't psychopathic intending that they want to spread, verses sociopathic where they don't give a damn?

I think the stories of spitting are far and few in between. The tale of apathy, however, seems extremely widespread.
 
That Lancet paper on chloroquine has been retracted. That's the observational one looking at past data from various countries and it said there was higher mortality for chloroquine use. The authors got their data from this private firm Surgisphere who won't release their data for auditing, claiming proprietary reasons. It does look like they are scammers. Another paper was retracted that used their data.

Retraction—Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis - The Lancet

Lancet, NEJM retract Covid-19 studies that sparked backlash - Stat

Meanwhile, there was another study released last week that said chloroquine doesn't stop infection.

Study: Hydroxychloroquine doesn't prevent Covid-19 infection if exposed - Stat

There are still other ongoing random trial studies on chloroquine, so it will be sorted out eventually whether it does any good.
 
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Worldtraveller said:
southernhybrid said:
lpetrich said:
People who ignore social distancing rules may have psychopathic personality traits, study finds

The results:
Click to expand...


If that's true, most of the people in my small city have psychopathic traits. I think I refer to it more as ignorance or denial. I tried to convince a nurse friend that she should keep wearing her mask when she goes to the store etc. She is a Trump supporter and a conservative Christian. I've never thought of her as a psychopath, just a clueless victim of brainwashing.
Click to expand...
Trump supporter and conservative christian? Almost definitely a sociopath (not psychopath, if I remember the distinction correctly).
Click to expand...

No, the woman isn't a sociopath. I worked with her for a couple of months. I've seen her put her own health in danger to help a falling patients. That was stupid, imo, but it wasn't a sign of sociopathy. I call it stupid because if she hurt herself, she would no longer be able to care for her other patients. I've finally come to the conclusion that people like her totally lack any critical thinking skills. They might be bright but they lack the ability to analyze things well.

Anyway, the nurse is a very caring person, generally speaking. She's just totally brainwashed when it come to religion and politics. So, I'm not about to say that all Trump supporters are sociopaths. Some of my former patients who were in their 90s voted for Trump because they received literature in the mail that had conspiracy theory claims about Clinton. Older people are often easy to manipulate, so they believed the bullshit about Hillary. Ignorance and stupidly aren't the same as sociopathy.

Now, my wealthy brother in law does exhibit sociopathic symptoms. He voted for Trump because he wanted a tax break. He still supports him after all the damage he's done to the country. Last week, when my husband asked him how his dental practice was doing after the COVID lock down, he replied with a photo of himself and a woman. who was about 30 years younger than him, sitting in a restaurant. Then he texted, "COVID-19 has been very, very good to me. I've got patients booked for three months" So, in other words, safety be damned. I"m making lots of money and screwing women half my age. Who cares about the people who are suffering!

I would hate to know that my dentist was being so careless in the midst of a pandemic.
 
We've become acclimated to living with crazy people. Just because we've become acclimated doesn't mean the people aren't crazy. Being a little bit christian is certainly a little bit crazy. it's not enough to put someone in the psyche ward with a pathology but to believe some of the crazy stuff that is christian is certainly to be a little bit crazy. Singing songs to invisible people living in the sky is some pretty crazy shit.
 
I think it is funny how a thread original started to mock media over-reaction to an outbreak overseas evolved into an historic political under reaction to a pandemic, that is actually being more and more under-reacted to as the pandemic begins its next phase of killing Americans. Did I say funny, I meant depressing.
blastula said:
Major study finds steroid reduces deaths in patients with severe Covid-19 - Stat

In patients given dexamethasone, a cheap, widely available steroid, deaths in severe cases declined by a third for those on ventilators and by 20% for those on oxygen. This is just from a press release, no paper, so take it with some caveats, but it is from Oxford.
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It is good news, though the percentage helped seems small.
 
That's simply NOT possible. England has socialized medicine and there are simply no innovations or research that come from socialized medicine. This MUST be fake. ;) Next you'll try and convince me that Canada has solutions.
blastula said:
Major study finds steroid reduces deaths in patients with severe Covid-19 - Stat

In patients given dexamethasone, a cheap, widely available steroid, deaths in severe cases declined by a third for those on ventilators and by 20% for those on oxygen. This is just from a press release, no paper, so take it with some caveats, but it is from Oxford.
Click to expand...
 
I read somewhere that they think it might be that the dexamethasone stops cytokine storms. Of course, it's good that such an old cheap drug helps a percentage of the sickest, but we are still mostly clueless about this virus. Worse, there are too many people who are now in denial about it. Some conservatives are still saying that the entire thing is a hoax. More sings of the dumbing down of the country. Actually, we're not the only country who is treating this pandemic as if it's not serious. The whole world has gone insane.
 
southernhybrid said:
I read somewhere that they think it might be that the dexamethasone stops cytokine storms. Of course, it's good that such an old cheap drug helps a percentage of the sickest, but we are still mostly clueless about this virus. Worse, there are too many people who are now in denial about it. Some conservatives are still saying that the entire thing is a hoax. More sings of the dumbing down of the country. Actually, we're not the only country who is treating this pandemic as if it's not serious. The whole world has gone insane.
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Indeed. And Fauci's drug, remdesivir works in much the same situations for only $3999 more per dose!
 
southernhybrid said:
I read somewhere that they think it might be that the dexamethasone stops cytokine storms. Of course, it's good that such an old cheap drug helps a percentage of the sickest, but we are still mostly clueless about this virus.
Click to expand...

Yeah, it suppresses the immune system, which is why it works later in the disease where immune response is the problem, and which also means it can be used in a timely manner. Whereas antivirals like remdesivir have to be used early after infection to be effective, because the point is to stop replication, but most people aren't seeking treatment early enough to be helped much by antivirals.
 
There has been a mutation. A single point change. Paper not peer reviewed yet.
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that is causing the COVID-19 pandemic across the world has undergone a genetic mutation in the density of functional spikes on the virus, says a new study. This has led the virus to become highly infectious and easily transmissible between humans.

The study from Scripps Research is titled, “The D614G mutation in the SARS-CoV-2 spike protein reduces S1 shedding and increases infectivity.” It is available pre-print prior to the peer review process on the open-access site bioRxiv*.
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Antibodies to the previous non-mutated virus do not work on the mutated version.
/US-and-European-SARS-CoV-2-mutation-enhances-transmission-increases-infectivity.aspx

[YOUTUBE]https://youtu.be/8B-rk5VUcLo?t=925[/YOUTUBE]
 
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They discussed that preprint on the TWIV podcast, and they were very skeptical about the conclusion that this mutation has made the virus more infectious. The problems noted were that they used a pseudovirion and with cell cultures not humans nor even animals. It's possible it could be more infectious but this study is not enough to show it. It's too difficult to do the right experiment needed.

TWiV 628 June 18, 2020 starting about 10 minutes in.
 
George S said:
There has been a mutation. A single point change. Paper not peer reviewed yet.
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that is causing the COVID-19 pandemic across the world has undergone a genetic mutation in the density of functional spikes on the virus, says a new study. This has led the virus to become highly infectious and easily transmissible between humans.

The study from Scripps Research is titled, “The D614G mutation in the SARS-CoV-2 spike protein reduces S1 shedding and increases infectivity.” It is available pre-print prior to the peer review process on the open-access site bioRxiv*.
Click to expand...
Antibodies to the previous non-mutated virus do not work on the mutated version.
/US-and-European-SARS-CoV-2-mutation-enhances-transmission-increases-infectivity.aspx

[YOUTUBE]https://youtu.be/8B-rk5VUcLo?t=925[/YOUTUBE]
Click to expand...

Maybe it's too early in the morning but I'm not finding where it says the new variant is resistant to antibodies.
 
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