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Covid-19 miscellany

Legacy media still mute on John Hopkins study that found lockdowns etc to cause more harm than good;

A Johns Hopkins professor slammed his university and the mainstream media for downplaying a study conducted by economists at the university that found that COVID-19 lockdowns only reduced virus deaths by 0.2 percent. Dr. Martin Makary warned that 'people may already have their own narrative written' about the effectiveness of lockdowns in an interview with Tucker Carlson Wednesday night. 'Johns Hopkins itself did not even put out a press release about this study, and if you look at the media coverage, it's one of the biggest stories in the world today, and yet certain media outlets have not even covered it,' Makary told the Fox News host. Economists at the college carried out a meta-analysis and found that restrictions imposed in the spring of 2020 - including stay-at-home orders, compulsory masks and social distancing - only reduced COVID mortality by 0.2 percent. They warned that lockdowns caused 'enormous economic and social costs' and concluded that they were 'ill-founded and should be rejected as a pandemic policy instrument' going forward.

Daily Mail
You mean the study produced as part of their Studies in Applied Economics series? Written by three Economics Profs, one that works with the CATO Institute.

Gee, I wonder why the Daily Mail didn't catch that part.

Meanwhile, Liberal Arts professors determine spraying a house with water, not effective at saving a house from a fire. "You are ruining the house by drowning it in water, where is the sense in that?"
 
Back in June, my Eurasia Group colleagues and I took a look at how countries around the world were handling the initial outbreak of the pandemic. To do that, we focused on three key metrics: healthcare responses, political responses and financial responses. Plenty has changed since then. The world has developed and begun distributing different vaccines with varying degrees of efficacy; lockdowns have come and gone… and come back again; some countries have undergone crucial political transitions; and new virus mutations have begun to appear, to name just a few. With all that in mind, it’s high time to look back at the initial batch of countries that we deemed as standouts in the early days of the pandemic, to learn what their experiences have taught us as the pandemic continues to shape our daily lives.

Below, you will find quick updates on the countries, followed by three big lessons we need to take away as we head into the next phase of the pandemic.

So what do we learn looking back at all the ups and downs these initially strong responders have gone through over these intervening months?

Three things jump out.

1. Falling from Grace? Maybe

First, some of the standouts on this list weathered the initial storm so well that chasing vaccines in an ultra-competitive global environment weren’t a priority, or weren’t deemed an efficient use of limited resources. Most of the countries that fall into the category from this list—Taiwan, Singapore, South Korea, New Zealand, and Australia—have leadership and resources to attempt a course correct as necessary, but they need to be wary that a still-mutating virus carries very real risks for them both now and in the future. And given that all these countries are democracies—albeit with electorates with different thresholds for privacy intrusion by their government for the sake of public health—the possibility of population-fatigue from the extensive measures in place (or that will need to be snapped back after being given a brief return to normalcy) poses a real risk to the leaders currently in office, no matter how effectively they handled the early days of the crisis. Non-democracies have to worry about the same thing, but their threshold for social instability threatening their hold on power is higher.



2. Zeroes to Heroes

Second, there were some countries left off the initial list that we wrote back in June because of their lackluster response in the beginning of the pandemic, but that have since managed to acquit themselves well by vaccinating their populations at impressive clip—Israel and the United Kingdom are the poster children for this category, and the United States even deserves an honorable mention. That’s obviously excellent news for the sake of their citizens (though it remains to be seen how much it will help the political fortunes of U.K. Prime Minister Boris Johnson and Israeli Prime Minister Bibi Netanyahu, both of whom are dealing with other political problems aside from those caused by the pandemic; former President Donald Trump lost election largely on the back of pandemic mismanagement), and shows it’s possible to overcome early missteps in pandemic responses.



3. Leadership Matters

Obviously, not all countries started from the same place in terms of healthcare capacity, political systems or financial resources when the pandemic first struck, realities that certainly played out over the course of the last year. Our initial list was comprised mostly of open democracies (save the UAE) given the metrics we were using in June, but countries like Vietnam and China were strong contenders for inclusion back then as well, and have continued to outperform as the pandemic drags on. Which brings us to the critical point—we’ve seen strong pandemic responses from countries struggling with their finances (see Greece) while seeing the richest country in the world (the United States) struggle mightily with the same pandemic. More than that, we’ve seen successful responses from repressive regimes like Vietnam and China, and we’ve also seen successful responses from strong democracies like New Zealand and Australia, among others. Which tells us that it’s not money or political orientation alone that leads to successful country responses—leadership is critical, and the ability to create a shared sense of commitment and sacrifice is essential. Those leaders who took the threat most seriously early on and relied on science to guide the policy responses are the ones that have (so far) fared the best. Leadership matters, and the ongoing pandemic is the strongest argument we’ve seen for that in generations.
 
Yes, apparently the reality where you couldn't figure out 10% > 1/15.
Your poverty of imagination betrays you. There was going to be another COVID wave. Another COVID wave could have been a mutation of delta that was as infectious as omicron is now and as deadly as delta.

Your counterfactual reference point is "imagine if omicron had not appeared, and no other mutations, and no other waves of previous COVID disease".

Well, no fucking shit it would have been better.
Then don't oppose the things that make it better.
If you are telling me to endorse the government forcing medical procedures on unwilling persons, solely for the benefit of others: I am not going to endorse that.

COVID was not over after the last delta wave
Because evil people and/via their stupid victims.
Irrelevant. There was always going to be another wave(s).

It is a blessing that the current wave is omicron and not delta or an even more deadly variant. Omicron has displaced delta
... No, it isn't. 10% > 1/15. Omicron displaced Delta with a more deadly variant that accomplishes it's deadliness by being 15x as likely to mutate. I'm living in reality where I recognize the only reason that has not happened is entirely accidental and NOTHING is preventing a more deadly variant that escapes vaccines again.
Incorrect. Omicron itself is reducing the likelihood that a more deadly virus that is just as contagious as omicron emerges. Omicron is occupying the biological niche.

The only thing we are at all protected from is the "long term success" of that variant.... And in this situation it would only lack long term success because of how many people it would kill.

We need to do everything in our power to prevent it from mutating again, as much as is within our power.
Irrelevant to the statement I made that triggered Elixir.

 
Yes, apparently the reality where you couldn't figure out 10% > 1/15.
Your poverty of imagination betrays you. There was going to be another COVID wave. Another COVID wave could have been a mutation of delta that was as infectious as omicron is now and as deadly as delta.

Your counterfactual reference point is "imagine if omicron had not appeared, and no other mutations, and no other waves of previous COVID disease".

Well, no fucking shit it would have been better.
Then don't oppose the things that make it better.
If you are telling me to endorse the government forcing medical procedures on unwilling persons, solely for the benefit of others: I am not going to endorse that.

COVID was not over after the last delta wave
Because evil people and/via their stupid victims.
Irrelevant. There was always going to be another wave(s).

It is a blessing that the current wave is omicron and not delta or an even more deadly variant. Omicron has displaced delta
... No, it isn't. 10% > 1/15. Omicron displaced Delta with a more deadly variant that accomplishes it's deadliness by being 15x as likely to mutate. I'm living in reality where I recognize the only reason that has not happened is entirely accidental and NOTHING is preventing a more deadly variant that escapes vaccines again.
Incorrect. Omicron itself is reducing the likelihood that a more deadly virus that is just as contagious as omicron emerges. Omicron is occupying the biological niche.

The only thing we are at all protected from is the "long term success" of that variant.... And in this situation it would only lack long term success because of how many people it would kill.

We need to do everything in our power to prevent it from mutating again, as much as is within our power.
Irrelevant to the statement I made that triggered Elixir.

There is STILL going to be another COVID wave. More than one. If we are lucky, smaller waves, but they are coming.
 
Yes, apparently the reality where you couldn't figure out 10% > 1/15.
Your poverty of imagination betrays you. There was going to be another COVID wave. Another COVID wave could have been a mutation of delta that was as infectious as omicron is now and as deadly as delta.

Your counterfactual reference point is "imagine if omicron had not appeared, and no other mutations, and no other waves of previous COVID disease".

Well, no fucking shit it would have been better.
Then don't oppose the things that make it better.
If you are telling me to endorse the government forcing medical procedures on unwilling persons, solely for the benefit of others: I am not going to endorse that.

COVID was not over after the last delta wave
Because evil people and/via their stupid victims.
Irrelevant. There was always going to be another wave(s).

It is a blessing that the current wave is omicron and not delta or an even more deadly variant. Omicron has displaced delta
... No, it isn't. 10% > 1/15. Omicron displaced Delta with a more deadly variant that accomplishes it's deadliness by being 15x as likely to mutate. I'm living in reality where I recognize the only reason that has not happened is entirely accidental and NOTHING is preventing a more deadly variant that escapes vaccines again.
Incorrect. Omicron itself is reducing the likelihood that a more deadly virus that is just as contagious as omicron emerges. Omicron is occupying the biological niche.

The only thing we are at all protected from is the "long term success" of that variant.... And in this situation it would only lack long term success because of how many people it would kill.

We need to do everything in our power to prevent it from mutating again, as much as is within our power.
Irrelevant to the statement I made that triggered Elixir.

There is STILL going to be another COVID wave. More than one. If we are lucky, smaller waves, but they are coming.
They may be, but the waves will be less deadly than they would have been if this wave had been a delta mutation, for example. Being infected with omicron gives you protection against delta (and possibly other variants, including possible future variants), and omicron is occupying the biological niche that will hopefully crowd out deadlier variants. Indeed, just this morning I was reading that most of the people infected with omicron do not know it - the fatality rate is probably much lower than even 1/10 of delta.
 
Lockdowns ain't lockdowns.

There are weak lockdowns, where people are told not to do A, B, and C, but are still asked (or permitted) to do X, Y and Z.

Then there are draconian lockdowns, where people are told not to leave their homes other than for immediately life sustaining essentials, such as obtaining food or medical needs.

Orthogonal to these lockdown rulesets, however, is compliance. A lockdown is a set of rules; But its effectiveness is a combination of how restrictive the rules are and how diligently they are followed.

Trying to determine how effective lockdowns are by looking only at what the rules were is futile; The important question is 'how effectively did people actually isolate from one another?'.

Hence the apparent anomaly in Australia, where Melbourne had stricter rules than Sydney, but less success in containing the disease.

The difference was the demographic in which the majority of cases occurred.

Sydney cases tended to be amongst 'white collar' workers, who could telework, or who had permanent and/or salaried jobs such that obeying the rules and staying home was a minor burden.

Melbourne cases were far more prevalent amongst the 'blue collar' workforce, many of them in casual employment, for whom working from home is not possible, and to whom the loss of a day's work implies the loss of a day's pay.

Tell these latter people that they must stay home, and they will respond by asking 'who is paying?'. If there's no easy, quick, and dependable system in place to compensate them for loss of wages, they will go to work regardless of the rules.

The big outbreak in Brisbane that triggered a severe lockdown was centred on Indooroopilly, an affluent suburb with lots of white collar workers. Many of those directly affected were physicians and surgeons; The lockdown had a significant impact on our hospitals due to the large numbers of senior staff who were in quarantine. But compliance was very high - these were people who could easily afford to miss a few weeks of income, and who could be expected to understand the epidemiological reasoning behind being told to do so.

The Brisbane lockdowns worked extremely well. Sydney's worked notably less well. Melbourne never really got on top of things, not because 'lockdowns don't work', but because 'lockdowns need compliance to work', and 'lockdowns need financial safety nets to achieve compliance amongst blue collar workers'.

Lockdowns don't work in the USA, because the USA is utterly pathetic at protecting its people against poverty.

If you want people to stay at home, you need to pay people to stay at home. Lockdowns don't work if they're all stick and no carrot.
 
Yes, apparently the reality where you couldn't figure out 10% > 1/15.
Your poverty of imagination betrays you. There was going to be another COVID wave. Another COVID wave could have been a mutation of delta that was as infectious as omicron is now and as deadly as delta.

Your counterfactual reference point is "imagine if omicron had not appeared, and no other mutations, and no other waves of previous COVID disease".

Well, no fucking shit it would have been better.
Then don't oppose the things that make it better.
If you are telling me to endorse the government forcing medical procedures on unwilling persons, solely for the benefit of others: I am not going to endorse that.

COVID was not over after the last delta wave
Because evil people and/via their stupid victims.
Irrelevant. There was always going to be another wave(s).

It is a blessing that the current wave is omicron and not delta or an even more deadly variant. Omicron has displaced delta
... No, it isn't. 10% > 1/15. Omicron displaced Delta with a more deadly variant that accomplishes it's deadliness by being 15x as likely to mutate. I'm living in reality where I recognize the only reason that has not happened is entirely accidental and NOTHING is preventing a more deadly variant that escapes vaccines again.
Incorrect. Omicron itself is reducing the likelihood that a more deadly virus that is just as contagious as omicron emerges. Omicron is occupying the biological niche.

The only thing we are at all protected from is the "long term success" of that variant.... And in this situation it would only lack long term success because of how many people it would kill.

We need to do everything in our power to prevent it from mutating again, as much as is within our power.
Irrelevant to the statement I made that triggered Elixir.

There is STILL going to be another COVID wave. More than one. If we are lucky, smaller waves, but they are coming.
More, if we are WISE, they will be small.

So, because metaphor wants to balk because higher order math is also seemingly alluding him, though seeing as how 10%>(1/15) is eluding him...

Vaccines prevent both the virulence and the impact of omicron. So do masks. Less than they do Delta but whatever.

By taking measures to test regularly, wear masks, be vaccinated, this spread of 15x gets lowered.

It is entirely the spread of 15x that means 15x more likely to mutate than the previous strain.

We do not know what form the mutation(s) will take. They may be more or less deadly.

We are close, but not there, on an Omicron vaccine.

The next variant can be anywhere from as deadly as the original to less deadly than Omicron, but it is likely to be treatable by Omicron vaccine, but only partially.

Therefore the faster we find an Omicron vaccine in terms of spread metrics (vaccines per infections) the fewer people will die.

If we let it just escape all willy-nilly before we can get an Omicron vaccine, that time comes far later in deaths AND mutations per vaccine time.

We are in an arms race with a dumb evolver. We are much smarter evolvers because we evolve with intent. We cannot win this arms race if we do not evolve with intent via vaccination strategy.
 
Lockdowns ain't lockdowns.

There are weak lockdowns, where people are told not to do A, B, and C, but are still asked (or permitted) to do X, Y and Z.

Then there are draconian lockdowns, where people are told not to leave their homes other than for immediately life sustaining essentials, such as obtaining food or medical needs.

Orthogonal to these lockdown rulesets, however, is compliance. A lockdown is a set of rules; But its effectiveness is a combination of how restrictive the rules are and how diligently they are followed.

Trying to determine how effective lockdowns are by looking only at what the rules were is futile; The important question is 'how effectively did people actually isolate from one another?'.

Hence the apparent anomaly in Australia, where Melbourne had stricter rules than Sydney, but less success in containing the disease.

The difference was the demographic in which the majority of cases occurred.

Sydney cases tended to be amongst 'white collar' workers, who could telework, or who had permanent and/or salaried jobs such that obeying the rules and staying home was a minor burden.

Melbourne cases were far more prevalent amongst the 'blue collar' workforce, many of them in casual employment, for whom working from home is not possible, and to whom the loss of a day's work implies the loss of a day's pay.

Tell these latter people that they must stay home, and they will respond by asking 'who is paying?'. If there's no easy, quick, and dependable system in place to compensate them for loss of wages, they will go to work regardless of the rules.

The big outbreak in Brisbane that triggered a severe lockdown was centred on Indooroopilly, an affluent suburb with lots of white collar workers. Many of those directly affected were physicians and surgeons; The lockdown had a significant impact on our hospitals due to the large numbers of senior staff who were in quarantine. But compliance was very high - these were people who could easily afford to miss a few weeks of income, and who could be expected to understand the epidemiological reasoning behind being told to do so.

The Brisbane lockdowns worked extremely well. Sydney's worked notably less well. Melbourne never really got on top of things, not because 'lockdowns don't work', but because 'lockdowns need compliance to work', and 'lockdowns need financial safety nets to achieve compliance amongst blue collar workers'.

Lockdowns don't work in the USA, because the USA is utterly pathetic at protecting its people against poverty.

If you want people to stay at home, you need to pay people to stay at home. Lockdowns don't work if they're all stick and no carrot.
JobKeeper payments commenced in Australia in March 2020. Blue collar workers in Melbourne had as much financial support as blue collar workers in Sydney.
 
Metaphor said:
Irrelevant. There was always going to be another wave(s)...as long as there were anti-vax plague rats.

FIFY
And since there were "anti-vax plague rats", there was always going to be another wave. So your fantasy that the last pre-Omicron wave would have been the last wave is, indeed, a fantasy.
 
There is STILL going to be another COVID wave. More than one. If we are lucky, smaller waves, but they are coming.
They may be, but the waves will be less deadly than they would have been if this wave had been a delta mutation, for example. Being infected with omicron gives you protection against delta (and possibly other variants, including possible future variants), and omicron is occupying the biological niche that will hopefully crowd out deadlier variants. Indeed, just this morning I was reading that most of the people infected with omicron do not know it - the fatality rate is probably much lower than even 1/10 of delta.
There is no warranty on the next variant being less harmful. Statistically, that is more likely, but while rolling a seven is the most likely value with two dice, that doesn't mean you are rolling sevens every roll. And while Omicron was much less harmful (in general), it still led to the second highest daily death toll during the pandemic in the US due to its outrageous transmissibility.

Additionally, Omicron does not have to be the lineage for the next variant. Delta could create a new one that is closer to itself and more contagious. A cousin of Beta or Gamma could as well. One other issue with Omicron is that it is so transmissible, any other mutation that could poke towards the more harmful side would already come with the benefit of high transmissibility.
 
There is STILL going to be another COVID wave. More than one. If we are lucky, smaller waves, but they are coming.
They may be, but the waves will be less deadly than they would have been if this wave had been a delta mutation, for example. Being infected with omicron gives you protection against delta (and possibly other variants, including possible future variants), and omicron is occupying the biological niche that will hopefully crowd out deadlier variants. Indeed, just this morning I was reading that most of the people infected with omicron do not know it - the fatality rate is probably much lower than even 1/10 of delta.
There is no warranty on the next variant being less harmful. Statistically, that is more likely, but while rolling a seven is the most likely value with two dice, that doesn't mean you are rolling sevens every roll. And while Omicron was much less harmful (in general), it still led to the second highest daily death toll during the pandemic in the US due to its outrageous transmissibility.

Additionally, Omicron does not have to be the lineage for the next variant. Delta could create a new one that is closer to itself and more contagious. A cousin of Beta or Gamma could as well. One other issue with Omicron is that it is so transmissible, any other mutation that could poke towards the more harmful side would already come with the benefit of high transmissibility.
I love the way you use the idea of poking around in the dark as a metaphor for what is happening.
 
Metaphor said:
Irrelevant. There was always going to be another wave(s)...as long as there were anti-vax plague rats.

FIFY
And since there were "anti-vax plague rats", there was always going to be another wave. So your fantasy that the last pre-Omicron wave would have been the last wave is, indeed, a fantasy.
Nobody expected it to be the last wave except the people who were so dumb they thought a dumb, fast, purely Darwinian evolver would burn itself out from transmission. Not even the evil people that consistently told them that would even remotely be likely as a result of letting a dumb fast Darwinian evolver go rampant.

Everyone who knows anything about epidemiology even as to a reasonable high school education on the matter knows that reducing the size and propagation of the wave as much as possible, so as to reduce all the deaths, is our primary goal.

Because asking nicely doesn't work, things need to get a little less "asking nicely".
 
Metaphor said:
Irrelevant. There was always going to be another wave(s)...as long as there were anti-vax plague rats.

FIFY
And since there were "anti-vax plague rats", there was always going to be another wave. So your fantasy that the last pre-Omicron wave would have been the last wave is, indeed, a fantasy.
Except the waves would have been further apart! Much further apart... and they'd been not nearly as high. Especially regarding hospitalization and death.
 
There is no warranty on the next variant being less harmful. Statistically, that is more likely, but while rolling a seven is the most likely value with two dice, that doesn't mean you are rolling sevens every roll. And while Omicron was much less harmful (in general), it still led to the second highest daily death toll during the pandemic in the US due to its outrageous transmissibility.
The world daily death rate, even with the vastly increased infection rate, has not reached the peak daily death rate from the delta wave, and omicron appears to have already peaked in a number of geographies.
Additionally, Omicron does not have to be the lineage for the next variant. Delta could create a new one that is closer to itself and more contagious.
Well, yes it could, and those infected with omicron could have protection against it as it does against the current strain of delta.

A cousin of Beta or Gamma could as well. One other issue with Omicron is that it is so transmissible, any other mutation that could poke towards the more harmful side would already come with the benefit of high transmissibility.
A more transmissible variant (of omicron) would probably crowd out current omicron, but omicron is very transmissible already and provides protection against itself (once you've had it obviously, which a very large number of unreported people do).
 
There is no warranty on the next variant being less harmful. Statistically, that is more likely, but while rolling a seven is the most likely value with two dice, that doesn't mean you are rolling sevens every roll. And while Omicron was much less harmful (in general), it still led to the second highest daily death toll during the pandemic in the US due to its outrageous transmissibility.
The world daily death rate, even with the vastly increased infection rate, has not reached the peak daily death rate from the delta wave, and omicron appears to have already peaked in a number of geographies.
For fuck sakes, stop using math and stats if you lack the understanding of what those things mean. Yes, Omicron less deadly. However, it led to the second highest daily death toll in the US because it made up for lack of killing power with bulk infections.
Additionally, Omicron does not have to be the lineage for the next variant. Delta could create a new one that is closer to itself and more contagious.
Well, yes it could, and those infected with omicron could have protection against it as it does against the current strain of delta.
That's fucking marvelous. And if Beta or Gamma has a baby?
A cousin of Beta or Gamma could as well. One other issue with Omicron is that it is so transmissible, any other mutation that could poke towards the more harmful side would already come with the benefit of high transmissibility.
A more transmissible variant (of omicron) would probably crowd out current omicron, but omicron is very transmissible already and provides protection against itself (once you've had it obviously, which a very large number of unreported people do).
Well golly. Mission Accomplished... again!
 
In the case of COVID19, the virus has mutated in those who are not vaccinated, so we have multiple strains active, some of which are less controlled by current vaccine.
The Omicron mutation is a blessing, given it has displaced Delta, gives protection against Delta for people who get Omicron, has a much, much, much lower rate of causing severe disease and death, and will result in the end of the pandemic.

The data out of South Africa is misleading. Omicron has about half the lethality of Delta. However, it kills slower, causing misleading measurements.
Incorrect. Omicron has 10% of the lethality of delta.

As I said, misleading. It takes longer to kill so comparing the death rate at a certain point in the wave to the Delta wave will produce an answer lower than reality.
 
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