With testosterone and estrogen, we know the effects of exposure. We have seen those effects, and the effects of having control over them, and those effects are broadly positive.
We know SOME of the effects of testosterone and estrogen ON THE BODIES THAT DEVELOPED TO PROCESS THEM AT THOSE LEVELS.
We know very little about the effects of cross-sex hormones, and what we do know indicates an increase in risk for many illnesses, including heart attack and stroke, as well as things like vaginal atrophy and earlier onset of dementia.
And also the effects on the bodies where their factories were removed.
We absolutely know the effect of the various sex hormones because we have observed the effects of those hormones on people since people had those hormones as a part of their biology.
We know the effects of testosterone because the fact is, we have centuries of documentation on the different experiences between people with testicles and eunuchs, at various ages of becoming eunuchs.
We know those effects and the fact is that the people taking these hormones know the effect.
You may take some great issue and insult from the fact that some people do not want ovaries or testicles, and you may wish to manufacture all sorts of reasons to deny them access, but we know the effects of an absence of sex hormones on the human body, too.
The fact is, I'm going to take your claims that people who have ovaries have improved health and outcomes and file it in the circular file because the same claim has been made to defend circumcisions and is just as spurious.
It's a claim based on fear, not even of the unknown, but of things you are willfully ignorant of.