Covid-19 miscellany

[repoman]

Since this got lost in whatever nonsense TSwizzle is talking about I will repost these questions:

Burning questions that I have are this:

Do the antibodies (and other immune response) created from the muscular injection of the vaccine reach the nasal cavities at all? If not, was this known during the clinical trials?

For a natural infection by covid, either by vaxxed or non vaxxed, is there an immune response groundwork being laid in the upper respiratory system that is NOT done by the vaccination response?


Will a previously infected person exposed to delta have a lower load in their nasal passage than one who was vaxxed but not infected?

If this is not being found out AT THIS POINT that is totally crazy and negligent!

Will nasal vaccines do what our response to the virus already does, but the current vaccines do not?


I think that this is good news, the current vaccines will almost stop all serious illness and nasal vaccines MIGHT be able to stop transmission.

 

[Jimmy Higgins]

Not to mention that isolating children is fucking TERRIBLE.

And yet this has been the policy over the last 15 months in California. Public schools have been closed. Private schools in California have somehow managed to have in person tuition. My goodness, would you believe that California governor Newson (insufferable prick) has his kids in private schools for in person tuition? The damage being done to these kids is deliberate abuse for political reasons. The teachers union in LA County steadfastly refused to go back into the classrooms. Kids were forbidden to play sports, even outdoor sports.

It's child abuse. The people that are doing this are evil.

Getting a bit hysterical there.

 

[T.G.G. Moogly]

Just thought about medical insurance companies. What are they thinking? Should not severe stupidosis be on the list of preexisting conditions?
How much it costs them now to keep these people in ICU for weeks and weeks?

Shhhhh. And stop being so pragmatic and rational. Anti-vaxxers don't think like this. Better we think about their extended stays in hospitals as a kind of public service to the less intelligent.

Reminds me of my very conservative friend who was always bashing liberals and democrats. Then his niece overdosed and ended in ICU owing a million dollars. Of course he defended her actions and the fact that she was a welfare recipient and therefore could not pay.

The stupid is very, very, very strong in some people.

 

[Harry Bosch]

Just thought about medical insurance companies. What are they thinking? Should not severe stupidosis be on the list of preexisting conditions?
How much it costs them now to keep these people in ICU for weeks and weeks?

Really interesting point. However, there are many other examples of stupidosis that are treated and covered by medical insurance: smoking, motorcycle without a helmet, and etc.

 

[Toni]

Students suing University of Indiana seeking immediate relief from SCOTUS to block rule requiring vaccination or masks/dual weekly testing while this wrestles in the lower courts. The odd thing is IU allows a student to choose, vaccine or mask/testing. Students are effectively saying they have their rights to their body and shouldn't be held accountable for their choices. And it ain't just me.

It gets a little crazier from a political standpoint..
I ponder whether SCOTUS (ultra-right religious wing of it) kind of fears this angle as its potential implication on Roe v Wade and any attempt to end it.

Seriously, what is so precious about your 11 year old? Why don't you isolate the precious 11 year old?

Yes, this is the problem: you are not educated on this topic. Stop listening to Fox News, and educate yourself. I'm not always going to spoonfeed everything to you. But I'll help you here: kids 12 and under aren't medically cleared yet for the vaccine.

You still trying to get blood from a stone?

Quibble: there IS no University of Indiana. It's Indiana University.

I was really happy and surprised when Indiana University issued the vaccine mandate. Those challenges are very much expected but I doubt will win over the mandate. Universities can and do require routine vaccination for all students--one must provide one's vaccine record in order to attend. Other employers, particularly medical providers/facilities routinely require vaccination such as influenza vaccine and Hep B and Hep A vaccines and now those who have not previously required COVID vaccines are starting to do so.

Attendance at any university is voluntary, not mandatory. If students do not wish to be vaccinated, they 100% have the ability to refuse vaccination and decline to enroll or be on campus.

 

[repoman]

Reassuring study from Cell

https://www.cell.com/cell-reports-medicine/pdfExtended/S2666-3791(21)00203-2

 

[Elixir]

Reassuring study from Cell

https://www.cell.com/cell-reports-medicine/pdfExtended/S2666-3791(21)00203-2

View attachment 34753

I am sadly unable to glean much from those graphs or the scatter charts at the link. The extent of the "good news" does seem somewhat limited according to the authors.

Our findings show
that most COVID-19 patients induce a wide-ranging immune de-
fense against SARS-CoV-2 infection, encompassing antibodies
and memory B cells recognizing both the RBD and other regions
of the spike, broadly-specific and polyfunctional CD4+ T cells,
and polyfunctional CD8+ T cells. The immune response to natu-
ral infection is likely to provide some degree of protective immu-
nity even against SARS-CoV-2 variants because the CD4+ and
CD8+ T cell epitopes will likely be conserved. Thus, vaccine in-
duction of CD8+ T cells to more conserved antigens such as
the nucleocapsid, rather than just to SARS-CoV-2 spike anti-
gens, may add benefit to more rapid containment of infection
as SARS-CoV-2 variants overtake the prevailing strains.

But better than bad news, at least for SOME patients.

Our study popula-
tion was primarily outpatients with mild-to-moderate COVID-19
and thus we were unable to evaluate immune memory in those
with the extreme presentations, both asymptomatic and severe
COVID-19.

Overall, it provides no excuse to those previously infected, for not getting a vaccination.

 

[repoman]

Seems like the study is saying that adding MORE parts of the virus will be better.

In my inference, that is to have the vaccine response to become more well rounded as the natural infection is.

I concede that one shot for a previously infected seems to be a good compromise.

If you want to use the fact that we are in a huge world where people game the system and so on that is the reason every infected person should get two shots, ok...

Argument from practicality.

 

[repoman]

View attachment 34489

Actually in humans it is mostly used to prevent river blindness

 

[Elixir]

View attachment 34755

I'm sure the irony of that cannot possibly be lost on you...
(At least there IS evidence that it can prevent that particular cause of blindness. The cause afflicting the sheeple... not so much.)

 

[ZiprHead]

This type of reply along with your earlier mention of Trump tells me your position is not based on" science or data" but on ideology.

I'm not always going to spoonfeed everything to you. But I'll help you here: kids 12 and under aren't medically cleared yet for the vaccine.

Well keep the special one isolated at home until immortality is achieved.

Maybe it's time for you and the spreaders to stay home instead of the smart people.

 

[Loren Pechtel]

Another dead denier:

https://www.bbc.com/news/uk-england-dorset-58080116

There are a LOT of those…

Texas has seen nearly 9,000 COVID-19 deaths since February. All but 43 were unvaccinated people.

I'm talking about those who actively deny--this guy was posting videos about how it wasn't that bad after he caught it--not merely the refusers who aren't making a spectacle of it.

 

[Loren Pechtel]

Well here’s a twist.

False flag alert!

This shows up on Gab--and nowhere else.

No twist, this is the QOP lying as usual.

 

[Loren Pechtel]

You're being dramatic. If you don't want to get vaccinated (or if you can't get vaccinated for medical reasons): isolate yourself and/or wear a mask. Stay away from my 11-year old who can't get vaccinated. Protect others. Is that really too much to ask??!

And if they already had a lab verified infection and lab verified antibodies?

Not only that, vaccinated people are now passing delta around.

Has the transmission of delta by and viral load of the previously infected even been studied?

It would be ironic if it is safer to be around the previously infected than non infected, vaccinated people.

Any evidence there are more delta infections amongst the vaccinated than amongst those previously infected with another variant? Of course prior infection with delta would provide better protection because the vaccine isn't specifically targeted on delta.

 

[bilby]

An interesting article about the way Covid Delta spreads in schoolchildren, from the Taringa/Indooroopilly outbreak here in Brisbane.

https://www.brisbanetimes.com.au/national/queensland/the-queensland-delta-outbreak-supercharged-by-kids-and-its-lessons-for-australia-20210804-p58fmv.html

This outbreak is very well understood, with full viral genome sequencing and detailed contact tracing having been achieved for every person involved. This is happening in a city with no other Covid cases to 'muddy the waters'; Every case in Brisbane is directly linked to this single outbreak.

The remaining mystery is how the index case, a 17 year old girl, contracted the virus which was brought into Australia by two international travelers, both of whom were in quarantine. The leading hypothesis is that a medical student who is also the girl's tutor may have carried the virus from Sunshine Coast Hospital, where one of the overseas travelers was being treated, but that link has not been adequately demonstrated so far.

The vast majority of cases are at a half dozen schools, all of which are attended by children of upper middle class wealthy families in the inner West. One strange effect of this has been a significant doctor shortage in our hospitals, as many surgeons and medical specialists have been quarantined due to their children attending one or more of these schools.

It is very clear from this outbreak that, despite the disease usually being mild in children, they are very important and significant vectors, and a major factor in transmission to adult patients, where the disease is far more serious.

 

[Elixir]

Any evidence there are more delta infections amongst the vaccinated than amongst those previously infected with another variant? Of course prior infection with delta would provide better protection because the vaccine isn't specifically targeted on delta.

Would there be evidence for it if that were the case?
I know there are ongoing monitoring programs (28 of them iirc) involving tens of thousands of individual volunteers whose behavior is reported in detail and who get tested 1-3x/wk and sequences run on infected individuals. Hopefully these ongoing studies will alert us to waning vaccine efficacy and stuff like that. But it's not enough (yet) to say that within a given community or population, transmission to or from infected asymptomatic vaccinated people is more prevalent or less prevalent than from the un-vaxed.

There are also questions about re-infections - do re-infected people carry similar viral loads (and therefore similar transmission possibility) as vaccinated people? Do they get more sick or less sick?

Some of this stuff is only going to emerge in retrospect.

 

[ZiprHead]

[TWEET]<blockquote class="twitter-tweet"><p lang="en" dir="ltr">Shameless Human Misinformation Vector Sen. Rand Paul (R-KY) claims Democrats are "plucking" kids with COVID from the border "and putting them all over the United States as if they're wishing to seed the country with a new variant." <a href="https://t.co/MvFp44ge8C">pic.twitter.com/MvFp44ge8C</a></p>— The Recount (@therecount) <a href="https://twitter.com/therecount/status/1423325205779386373?ref_src=twsrc%5Etfw">August 5, 2021</a></blockquote> <script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>[/TWEET]

Fucking moron.

 

[marc]

[TWEET]<blockquote class="twitter-tweet"><p lang="en" dir="ltr">Shameless Human Misinformation Vector Sen. Rand Paul (R-KY) claims Democrats are "plucking" kids with COVID from the border "and putting them all over the United States as if they're wishing to seed the country with a new variant." <a href="https://t.co/MvFp44ge8C">pic.twitter.com/MvFp44ge8C</a></p>— The Recount (@therecount) <a href="https://twitter.com/therecount/status/1423325205779386373?ref_src=twsrc%5Etfw">August 5, 2021</a></blockquote> <script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>[/TWEET]

Fucking moron.

MAGAts: OMG! The libs are using illegals to spread the virus everywhere!!

Reasonable person: so then shouldn’t you get the vaccine to protect yourself?

MAGAts: What? No, the virus is no more dangerous than the flu.

 

[repoman]

In reality it is border patrol working with catholic charities

https://twitter.com/BillFOXLA/status/1422193154615398410

 

[barbos]

Just thought about medical insurance companies. What are they thinking? Should not severe stupidosis be on the list of preexisting conditions?
How much it costs them now to keep these people in ICU for weeks and weeks?

Really interesting point. However, there are many other examples of stupidosis that are treated and covered by medical insurance: smoking, motorcycle without a helmet, and etc.

Your examples are stage 1 stupidosis, they are local, don't have a tendency to spread/metastasize and don't affect insurance companies bottom line as much.
And I understand they do charge these mild sufferers of stupidosis premium. So what are they thinking now? is t it not the time to be evil?