I fully concede that there is an *overall* gender binary
I personally don't disagree that
statistically, we end up seeing bimodality, and that this is a consequence of the accident of anisogamy.
Clearly, many orderings of flesh do not yield the ability to reproduce in the same way that those "more normally comorbid" do. This in turn leads to a relative uncommonness of such folks.
It comes down to the fact that while there is no obligation to reproduce, not reproducing will generally cause the biological differences and novelties to dead-end.
it's not that it can't or even "shouldn't" end up outside the expectations of others. It is merely that "it won't for very long".
My biggest problem is that when some folks see someone who will live and die and their flesh is both something new and something that will vanish forever, that this is some kind of natural sign or judgment over the transient existence of that person. They conclude that there is some "disorder", not of themselves but someone else.
But there is no "ought" here.
Personally I would call them rather "differences in sexual development" rather than "disorders in sexual development".